After discovering his star dancer is expecting and can't perform, film producer H.W. Workman and his publicist concoct a scheme to stage a college dance contest to find a new star.
A horse called Brilliant is the only one who knows the location of a gold mine. When Brilliant's owner is killed, the trio known as the Three Mesquiteers (Bob Steele, Tom Tyler and Jimmie Dodd) are mistakenly arrested for the murder.
It is now an accepted fact that the best of Johnny Mack Brown's Universal westerns were directed by the talented Joseph H. Lewis. Boss of Hangtown Mesa may not be in the same league as the Brown-Lewis classic Arizona Cyclone, but it comes awfully close. This time around, hero Steve Collins (Brown) comes to the aid of Betty Wilkins (Helen Deverell), who has taken over the telegraph-line business established by her uncle John (Henry Hall). The latter was murdered by outlaws who don't cotton to having the territory linked up electronically with the rest of the world.
Deux conducteurs de bus, Algernon Shaw et Wellington Pflug, sont accusés, à la suite d'un malentendu, d'avoir volé leur propre bus. Pour échapper à cette situation délicate, ils fuient sur une île tropicale, où, malheureusement, d'autres mauvaises surprises les attendent…