Claire and David are on a trip to Offline Valley in order to disconnect from social networks and the pressures of modern-day society. They'll probably end up dead.
In the claustrophobic confines of a rural estate, a family struggles with their tangled web of hereditary diseases. Among them is Alessandro, a young man with epilepsy and paranoid tendencies. Feeling burdened by the numerous afflictions that plague his family, he decides to murder them all.
Stu's stag do in South America goes bad when Greg collapses at customs and is found to be full of cocaine. Arrested, the group are taken to an island prison run by cocaine-smuggling siblings, Selma and Branco. Things go from very bad to much worse.