Filmées en une seule prise sur la place de Lavapiés à Madrid, ces 20 histoires s'entrecroisent autour des thèmes de la conversation, de la communication et des mots.
Max is a Jack Russell dog genetically modified for criminal purposes so he is able to talk. Running away from the criminals he's working for, he is wounded, then saved by detective-wannabe Alberto, who is fire and house-hunting. They end up staying with Alberto's sister-in-law Marta and her two children. Thanks to them all, Alberto finally manages to be a detective, and he and Max establish their detective agency: Sabuesos.
Nacho Nieto, a journalist specialising in paranormal activity, is at a professional and personal low. After a failed suicide attempt he comes back to life accompanied by the ghost of his mentor, doctor Estrada, iconic communicator of mystery, who died more than 20 years ago.