Rodolfo runs into Ignacio, a high school friend who married his ex-girlfriend. On Day of the Dead, Ignacio throws a party and Rodolfo attends with a prostitute.
Newlyweds Mario and Diana discover they have no chemistry. She starts to fall in love with her boss and does not realize her husband also loves another person.
Biochemists Lourdes and Liliana work at a laboratory. One day, they steal a drug that has high levels of female hormones and give it to their oblivious husbands to force each of them to experience a day in the life of a woman.
Gonzalo pays his cousin Andres a visit to bring him terrible news: their grandfather has died and has left them out of his will. On that same day, one of Andres' neighbors asks them to stay at her apartment while she goes out.
Magnolia is left unconscious after being run over by a car. Julián and Jaime take advantage of the situation and call her family to say she has been kidnapped.