Au milieu du 21ème siècle et dans un des pays les plus violents pour les femmes, RUIDO raconte le parcours et la douleur d'une mère face à la disparition de sa fille et de sa propre vie.
Max is a Jack Russell dog genetically modified for criminal purposes so he is able to talk. Running away from the criminals he's working for, he is wounded, then saved by detective-wannabe Alberto, who is fire and house-hunting. They end up staying with Alberto's sister-in-law Marta and her two children. Thanks to them all, Alberto finally manages to be a detective, and he and Max establish their detective agency: Sabuesos.