Blaine Zuckerman

Dysfunctional in-laws on Thanksgiving are one thing, but a long-lost brother-in-law who sprouts leaves when he gets wet is a whole other can of cranberries.

Two-time Emmy Award-winner Megan Mullally, coming off eight seasons as wisecracking socialite Karen Walker on NBC's "Will & Grace," moves into the driver's seat as host for this daytime talk show. Each episode is an entertaining hour featuring a mix of celebrities, real people, music, and comedy. Megan will interview top celebrities and also introduce the world to guests of all kinds — from quirky characters to funny kids to offbeat experts.